Index of Diseases


Zellweger Syndrome

Definition: An autosomal recessive peroxisomal disorder that typically presents in the neonatal period and is usually fatal. Clinical features include hypotonia, dysmorphic skull and facial bones, visual compromise, multifocal seizures, hepatomegaly, biliary dysgenesis, and swallowing difficulties. Pathologically, there are migration deficits of the neocortex and degeneration of white matter tracts. Zellweger-like syndrome refers to conditions that phenotypically resemble neonatal Zellweger syndrome, but occur in childhood or adulthood (From Adams et al., Principles of Neurology, 6th ed, p946) Annotation: ID#: D015211

Zenker Diverticulum

Definition: A diverticulum at the upper end of the esophagus through the cricopharyngeal muscle. Annotation: inflamm divertic or diverticulitis: coord IM with DIVERTICULITIS (IM) ID#: D016672

Zollinger-Ellison Syndrome

Definition: A triad comprising intractable, sometimes fulminating, and in many ways, atypical ulcers; extremely elevated gastric acidity; and gastrin-secreting non-beta islet cell tumors, usually of the pancreas, but sometimes in other sites (e.g., the duodenum), which may be single or multiple, large or small, benign or malignant. (Dorland, 27th ed) Annotation: peptic ulcer with gastric hyperacidity & islet cell tumors; do not use /blood supply /chem /second /secret /ultrastruct ID#: D015043


Definition: Diseases of non-human animals that may be transmitted to man or may be transmitted from man to non-human animals. Annotation: usually dis from animal to man but includes also dis from man to animal; can be bact, fungal, viral or parasitic; avoid qualif: few apply; not a coord for every zoonotic dis: index as ZOONOSES only when discussed: TN 199 ID#: D015047

Zygomatic Fractures

Definition: Fractures of the zygoma. Annotation: ID#: D015051


Definition: Infection in humans and animals caused by fungi in the class Zygomycetes. It includes MUCORMYCOSIS and entomophthoramycosis. The latter is a tropical infection of subcutaneous tissue or paranasal sinuses caused by fungi in the order Entomophthorales. Phycomycosis, closely related to zygomycosis, describes infection with members of Phycomycetes, an obsolete classification. Annotation: fungus dis caused by various Zygomycetes; for dis caused by Mucorales, MUCORMYCOSIS is available ID#: D020096