Glossary of Bio-Medical Terms



Q beta Replicase

MS = An enzyme that catalyzes the replication of the RNA of coliphage Q beta. EC 2.7.7.-.

UI = D011777


Q Fever

MS = An acute infectious disease caused by COXIELLA BURNETII. It is characterized by a sudden onset of fever, headache, malaise, and weakness. In humans, it is commonly contracted by inhalation of infected dusts derived from infected domestic animals.

AN = caused by Coxiella burnetii

UI = D011778



MS = A personality assessment technique in which the subject or observer indicates the degree to which a standardized set of descriptive statements actually describes the subject. The term reflects "sorting" procedures occasionally used with this technique.

UI = D011779



UI = D011780



MS = The vital life force in the body, supposedly able to be regulated by acupuncture. It corresponds roughly to the Greek pneuma, the Latin spiritus, and the ancient Indian prana. The concept of life-breath or vital energy was formulated as an indication of the awareness of man, originally directed externally toward nature or society but later turned inward to the self or life within. (From Comparison between Concepts of Life-Breath in East and West, 15th International Symposium on the Comparative History of Medicine - East and West, August 26-September 3, 1990, Shizuoka, Japan, pp. ix-x)

AN = Qi defic goes here

UI = D019413



MS = The fraudulent misrepresentation of the diagnosis and treatment of disease.

UI = D011781



MS = Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.

UI = D011782



AN = human only: for animals use LITTER SIZE; relation to PREGNANCY: Manual 28.17.4

UI = D011783



AN = GEN or unspecified; prefer COLINUS & COTURNIX; note JAPANESE QUAIL see COTURNIX; IM; qualif permitted; diseases: coord IM with BIRD DISEASES (IM)

UI = D011784


Qualitative Research

MS = Research that derives data from observation, interviews, or verbal interactions and focuses on the meanings and interpretations of the participants (From Holloway and Wheeler, "Ethical issues in qualitative nursing research," Nursing Ethics, 1995 Sep; 2(3): 223-232).

UI = D036301


Quality Assurance, Health Care

MS = Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.


UI = D011785


Quality Control

MS = A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)

AN = NIM; no qualif

UI = D011786


Quality Indicators, Health Care

MS = Norms, criteria, standards, and other direct qualitative and quantitative measures used in determining the quality of health care.

UI = D019984


Quality of Health Care

MS = The levels of excellence which characterize the health service or health care provided based on accepted standards of quality.


UI = D011787


Quality of Life

MS = A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.

UI = D011788


Quality-Adjusted Life Years

MS = A measurement index derived from a modification of standard life-table procedures and designed to take account of the quality as well as the duration of survival. This index can be used in assessing the outcome of health care procedures or services. (BIOETHICS Thesaurus, 1994)

AN = DF: note short X ref

UI = D019057


Quantitative Structure-Activity Relationship

MS = A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity information gathered from a series of similar compounds.


UI = D021281


Quantitative Trait Loci

MS = Locations, on the GENOME, of GENES or other genetic elements that encode or control the expression of a QUANTITATIVE TRAIT.

UI = D040641


Quantitative Trait, Heritable

MS = A characteristic showing quantitative inheritance such as SKIN PIGMENTATION in humans. (From A Dictionary of Genetics, 4th ed)

UI = D019655


Quantum Theory

MS = The theory that the radiation and absorption of energy take place in definite quantities called quanta (E) which vary in size and are defined by the equation E=hv in which h is Planck's constant and v is the frequency of the radiation.

UI = D011789



MS = Restriction of freedom of movement of individuals who have been exposed to infectious or communicable disease in order to prevent its spread; a period of detention of vessels, vehicles, or travelers coming from infected or suspected places; and detention or isolation on account of suspected contagion. It includes government regulations on the detention of animals at frontiers or ports of entrance for the prevention of infectious disease, through a period of isolation before being allowed to enter a country. (From Dorland, 28th ed & Black's Veterinary Dictionary, 17th ed)

AN = human or animal; /vet permitted

UI = D011790



MS = Quartz (SiO2). A glassy or crystalline form of silicon dioxide. Many colored varieties are semiprecious stones. (From Grant & Hackh's Chemical Dictionary, 5th ed)

AN = a form of silicon dioxide

UI = D011791



MS = A plant genus of the family SIMAROUBACEAE. Members contain quassinoids. Quassia simarouba has been reclassified as SIMAROUBA.

AN = QUASSIA SIMAROUBA see SIMAROUBA is also available; coord with specific PLANT COMPONENTS term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29

UI = D032271



MS = A group of degraded TRITERPENES which have lost ten carbons (8 from the side chain, C17, and one from C4) so have C20 skeletons which could be misinterpreted as DITERPENES. They especially occur in plants of the SIMAROUBACEAE family.

UI = D036702



MS = A province of eastern Canada. Its capital is Quebec. The region belonged to France from 1627 to 1763 when it was lost to the British. The name is from the Algonquian quilibek meaning the place where waters narrow, referring to the gradually narrowing channel of the St. Lawrence or to the narrows of the river at Cape Diamond. (From Webster's New Geographical Dictionary, 1988, p993 & Room, Brewer's Dictionary of Names, 1992, p440)

AN = a province of eastern Canada

UI = D011792



MS = A state in northeastern Australia. Its capital is Brisbane. Its coast was first visited by Captain Cook in 1770 and its first settlement (penal) was located on Moreton Bay in 1824. The name Cooksland was first proposed but honor to Queen Victoria prevailed. (From Webster's New Geographical Dictionary, 1988, p996 & Room, Brewer's Dictionary of Names, 1992, p441)

AN = a state of Australia

UI = D011793



MS = A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.

UI = D011794



MS = A plant genus of the family FAGACEAE that is a source of TANNINS. Do not confuse with Holly (ILEX).

AN = coord with specific PLANT COMPONENTS term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29

UI = D029963



MS = Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

AN = coord IM with specific subject or group (IM)

UI = D011795



MS = A plant genus of the family ROSACEAE. Members contain SAPONINS.

AN = do not confuse X ref QUILLAJA SAPONARIA with the genus SAPONARIA; coord with specific PLANT COMPONENTS term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manual 26.29

UI = D031990



MS = An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.

UI = D011796


Quinacrine Mustard

MS = Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic acids in chromosomes.

AN = D25-26 qualif

UI = D011797



UI = D011798



UI = D011799



MS = 3-(Cyclopentyloxy)-19-nor-17 alpha-pregna-1,3,5(10)-trien-20-yn-17-ol. The 3-cyclopentyl ether of ETHINYL ESTRADIOL. After gastrointestinal absorption, it is stored in adipose tissue, slowly released, and metabolized principally to the parent compound. It has been used in estrogen replacement therapy. (From AMA Drug Evaluations Annual, 1992, p1011)

AN = "used in estrogen replacement ther"

UI = D011800


Quinic Acid

MS = An acid which is found in cinchona bark and elsewhere in plants. (From Stedman, 26th ed)

UI = D011801



MS = An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.

UI = D011802



MS = An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

AN = /biosyn permitted if by plant

UI = D011803



AN = do not confuse with QUINOLIZINES nor with QUINOLONES nor its X ref QUINOLINONES

UI = D011804


Quinolinic Acid

MS = A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.

UI = D017378


Quinolinic Acids

UI = D011805


Quinolinium Compounds


UI = D011806



AN = do not confuse with QUINOLINES

UI = D011807



MS = A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.

AN = do not confuse with QUINOLINES

UI = D015363


Quinone Reductases

MS = NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC (NAD(P)H DEHYDROGENASE (QUINONE)); is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.

UI = D011808



MS = Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.

UI = D011809



UI = D011810



MS = A dopamine D2/D3 receptor agonist.

UI = D019257



AN = human only; for animals use LITTER SIZE; relation to PREGNANCY: Manual 28.17.4

UI = D011811



UI = D011812


Quinuclidinyl Benzilate

MS = A high-affinity muscarinic antagonist commonly used as a tool in animal and tissue studies.

UI = D011813



MS = A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.

UI = D011814


Quisqualic Acid

MS = An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis.

UI = D016318